[PubMed] [CrossRef] [Google Scholar] 20. among the 4 organizations. Results The entire vaccination group got a considerably higher age compared to the non-vaccination group at analysis ( em P /em 0.05), and there is a big change in the route of transmitting between your two organizations ( em P /em 0.05). There have been no significant variations among the four organizations in sex, medical classification, and re-positive price of SARS-CoV-2 nucleic acidity recognition ( em P /em 0.05). All 97 kids had been vaccinated with inactivated vaccine, among whom 85 kids (88%) had been vaccinated with BBIBP-CorV Rabbit polyclonal to STAT6.STAT6 transcription factor of the STAT family.Plays a central role in IL4-mediated biological responses.Induces the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Sinopharm vaccine (Beijing Institute of Biological Items, Beijing, China). At one month after analysis, the booster vaccination group and the entire vaccination group got a significantly more impressive range of SARS-CoV-2 IgG antibody compared to the non-vaccination group ( em P /em 0.05), with 2 months after analysis, the entire vaccination group had a significantly more impressive range of SARS-CoV-2 IgG antibody compared to the non-vaccination group ( em P /em 0.05). For the entire vaccination group, the amount of SARS-CoV-2 IgG antibody at 2 weeks after analysis was significantly less than that LODENOSINE at one month after analysis ( em P /em 0.05). Conclusions Vaccination with inactivated SARS-CoV-2 vaccine includes a protecting impact against Omicron disease in kids. For kids vaccinated with 2 dosages from the vaccine who encounter Omicron infection, there could be a slight decrease in the known degree of SARS-CoV-2 IgG antibody at 2 months after diagnosis. Citation:Chinese language Journal of Modern Pediatrics, 2022, 24(7): 736-741 solid course=”kwd-title” Keywords: Coronavirus disease 2019, Omicron, IgG, Vaccination, Recovery stage, Kid 2019coronavirus disease 2019COVID-192severe severe respiratory symptoms coronavirus 2SARS-CoV-212021119COVID-19Omicron2Globe Wellness OrganizationWHOCOVID-195variant of concernVOCSARS-CoV-22022182SARS-CoV-2COVID-192VOC/OmicronBA.1430SARS-CoV-2COVID-19VOC/Omicron 1811426.5%SARS-CoV-2SARS-CoV-2COVID-19SARS-CoV-24spike proteinSSSARS-CoV-22S1S2S13neutralization testNT4NTSARS-CoV-2IgGSARS-CoV-2 IgG5-7COVID-19SARS-CoV-2 IgG 1.? 1.1. 20221827COVID-191140~17COVID-1914 d4SARS-CoV-2 IgG110COVID-194322901513COVID-1982022N050KY 1.2. COVID-19125 d12~30 d243 d31~52 dSARS-CoV-2 IgGSARS-CoV-2 1.3. SARS-CoV-2 IgGSARS-CoV-2 IgGG202110004/sign to cut-offS/COS/CO1.0 1.0 SARS-CoV-2Zybio5203050polymerase string reactionPCR24 h2PCRPCR Ct 40 1.4. SPSS 22.0%FisherBonferroniKruskal-Wallis em H /em BonferroniWilcoxon em P /em 0.05 2.? 2.1. 110COVID-1911.04101~1771/11064.5%91/11082.7%1412.7%SARS-CoV-21109788.2%90/11081.8%4SARS-CoV-2 em P /em 0.054 em P /em 0.05 em P /em =0.007 em P /em 0.05 em P /em 0.05 em P /em 0.051 1 4COVID-19 thead th align=”middle” design=”border-top:1px stable;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ ( em n /em =13) /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ ( em n /em =5) /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ ( em n /em =90) /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ ( em n /em =2) /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ em H /em /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ em P /em /th /thead [(%)]9(69)1(20)44(49)0(0)-0.133 [(), ]2(1~10)8(4~16)10(5~17)a 8(7~9)31.871 0.001 [(%)]1(8)0(0)5(6)0(0)-0.69612(92)4(80)73(81)2(100)0(0)1(20)12(13)0(0)/0(0)0(0)0(0)0(0) [(%)]a 13(100)5(100)51(57)2(100)-0.0210(0)0(0)33(37)0(0)0(0)0(0)6(7)0(0)SARS-CoV-2 [(%)]3(23)2(40)9(10)0(0)-0.093 [(), d]-30(20~185)48(22~239)56(54~58)5.1830.075 Open up in another window em class=”vocab-note” /em a em P /em 0.05 2.2. 9785/9788%1111%/11%2 2 97COVID-19% thead th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ ( em n /em =5) /th LODENOSINE th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ LODENOSINE colspan=”1″ ( em n /em =90) /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ ( em n /em =2) /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ ( em n /em =97) /th /thead 3(60)81(90)1(50)85(88)2(40)8(9)1(50)11(11)/0(0)1(1)0(0)1(1) Open up in another screen 2.3. 412SARS-CoV-2 IgG 901SARS-CoV-2 IgG842SARS-CoV-2 IgG412SARS-CoV-2 IgG em P /em 0.051SARS-CoV-2 IgG em P /em 0.052SARS-CoV-2 IgG em P /em 0.053 3 412SARS-CoV-2 IgG S/CO thead th align=”middle” design=”border-top:1px great;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ em H /em /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ em P /em /th /thead 1135802SARS-CoV-2 IgG7.5(0.07~27.4)144.3(63.3~229.4)194.5(73.1~255.9)a 207.5(192.7~222.3)a 34.8 0.001233762SARS-CoV-2 IgG2.09(2.02~35.97)215.0(117.5~222.6)189.6(8.7~261.3)a 173.8(152.5~195.1)8.70.034 Open up in another window em class=”vocab-note” /em a em P /em 0.05 2.4. 4SARS-CoV-2 IgG 7612SARS-CoV-2 IgG2SARS-CoV-2 IgG1 em P /em 0.0512SARS-CoV-2 IgG em P /em 0.054 4 4SARS-CoV-2 IgG S/CO thead th align=”center” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ ( em n /em =3) /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ ( em n /em =3) /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ ( em n /em =68) /th th align=”middle” design=”border-top:1px solid;border-bottom:1px solid;background-color:#D3DAEE;” rowspan=”1″ colspan=”1″ ( em n LODENOSINE /em =2) /th /thead 11.77(1.23~27.39)209.6(134.1~229.4)196.2(73.1~255.9)207.5(192.7~222.3)22.09(2.02~36.0)215.0(117.5~222.6)191.3(76.5~261.3)173.8(152.5~195.1) em Z /em -1.604-1.069-2.841-1.342 em P /em 0.1090.2850.0040.180 Open up in another window 3.? 202173~17SARS-CoV-29202242631333 628.51088.2%COVID-1914611 em Lancet /em Delta125~17BNT162b25~1113 SARS-CoV-2SS1415Seaman16SARS-CoV-2 DeltaBA.112SARS-CoV-2 IgG21SARS-CoV-2 IgGSARS-CoV-2 IgGWang15SBSARS-CoV-21SARS-CoV-2SARS-CoV-2 IgGSARS-CoV-2SARS-CoV-2 IgGSARS-CoV-2 IgG239 d1SARS-CoV-2 IgG173.1 S/COSARS-CoV-2 IgGSARS-CoV-2SARS-CoV-2Wang17323SARS-CoV-2SARS-CoV-2SARS-CoV-2 IgG21IgGSughayer18SARS-CoV-2 IgG120 d em Pediatrics /em 1920SARS-CoV-2 3~173SARS-CoV-2 IgGIgG12SARS-CoV-2 IgGSARS-CoV-2IgG 1. 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